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(1) identification or elucida-tion of a new drug target; (2) rational design of a new moleculebased on an understanding of biologic mechanisms and drugreceptor structure; (3) screening for biologic activity of large num-bers of natural products, banks of previously discovered chemicalentities, or large libraries of peptides, nucleic acids, and otherorganic molecules; and (4) chemical modification of a knownactive molecule, resulting in a me-too analog. it dilates the pupil and relaxes accommodationmore quickly pain pills online legally than atropine, yet the paralysis of adaptation andaccommodation is of shorter duration.— pam/yw of thenerve endings of secretory glands, smooth muscle fibres and inhibitoryapparatuses with decrease in the secretion of the skin, respiratoryand gastro'intestinal tract, with relaxation of the smooth musclesin the gastrointestinal and urinary tracts, also with relaxationof the iris and ciliary muscles giving rise to paralysis of accommodation and adaptation but increase in the intraocular tension.quickening of the pulse due to paralysis of the vagus endings.the respiratory and vasomotor centres in the medulla first stimu70 constrnmonal organic drugs.hied then depressed. in addition, the practical efficacy of adrug for achieving a therapeutic end point (eg, increased cardiaccontractility) may be limited by the drugs propensity to cause atoxic effect (eg, history of ambien fatal cardiac arrhythmia) even if the pain pills online legally drug couldotherwise produce a greater therapeutic effect. the dissolutionmethod developed has to demonstrate a correlation that isrelevant to the bioavailability of the dosage form. 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